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Restoring mannose metabolism enhances T-cell antitumor activity and limits exhaustion by promoting stem-like programs through preserving Tcf7 expression and epigenetic stemness, offering a potential strategy for improving ICT [389]

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PEPCK-M activity depends on mitochondrial GTP generated because of the activity of the GTP-specific isoform of succinyl CoA-synthetase (SCS-GTP) (87)

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Polymer-based nanoparticles such as Eudragit S100 and poly(n-butylcyanoacrylate) demonstrated targeted delivery with pH-sensitive release, suitable for colon cancer treatment, featuring particle sizes around 65165 nm and EE ranging from 4279%

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J.WinterG

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& Kinnari, T

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FDA-approved medication pathways require evaluation by licensed medical professionals

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