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H.MansonJ

Psychiatry Res Neuroimaging 325:111516

Wang, Melanoma-derived small extracellular vesicles remodel the systemic onco-immunity via disrupting hematopoietic stem cell proliferation and differentiation

The cleavage of APP by beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) generated a soluble sAPP ectodomain and a 99-amino-acid C-terminal membrane-bound fragment
Therefore, at higher levels, ROS are responsible for the damage of most of cellular macromolecules, whereas they exhibit signaling role at moderate levels
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N.RamanJ.SabaratnamV
