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However, the underlying mechanisms in disease progression are still unclear

These epialleles confer a 15-20% yield advantage under terminal drought conditions (Siddiqui et al., 2023)

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Andreeff M , Borthakur G, Zeng Z, Kelly MA, R-Y W, McQueen TJ, Y-H Q, Mak D, Burger JA, Daver NG, Pemmaraju N, Kadia TM, Jabbour E, Pierce S, Ravandi F, Garcia-Manero G, O'Brien SM, Cortes JE, Kantarjian HM, Konopleva M

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Furthermore, gene expression analysis of adipocytes differentiated from lipedema-derived stem cells (derived from Stages 13 of lipedema) revealed a significant upregulation of adipogenic markers, such as leptin and PPAR-, compared to healthy non-lipedema adipocytes suggesting an increased adipogenic differentiation potential in lipedema tissue ( Similar to obesity, researchers have observed increased collagen content in lipedema tissue, indicating that fibrosis is also a characteristic of lipedema (Kruppa et al., 2023)