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Discussion In this study, we hypothesized that overwhelming the antioxidant defenses with diamide in normoxic perfused hearts would trigger mitochondrial criticality [15], leading to lethal arrhythmias in isolated hearts

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Although it has not been approved by major regulatory bodies like the FDA, it is widely researched in the realms of regenerative medicine, sports medicine, and injury rehabilitation

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Trans-endothelial electrical resistance (TEER) was evaluated on hBMEC monolayers showing a value of 149.7 3.6 cm by day 6, indicating the formation of a tight barrier mimicking the BBB in an in vitro model, thereby confirming the validity of subsequent permeability study