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"If someone injects it under their skin, what are they getting?" During the COVID-19 pandemic, the FDA issued over a half-dozen warning letters to businesses promoting peptides with "immune-boosting powers." Then in 2023, the agency added nearly 20 peptides to a list of substances that should not be compounded due to safety risks

This is likely due to the interaction of positively charged mAbs with negatively charged cell surfaces and proteins, which can lead to receptor mediated uptake and facilitates the internalization and presentation of mAb-derived peptides by APCs

Acknowledgements A.A.G is supported by National Science Foundation Graduate Research Fellowship (NSF-GRFP) [Grant DGE - 1656518] and National Institute of Health (NIH) training grant [Grant 5T32GM113854]

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doi: 10.1016/j.nutos.2022.05.005 133

In manufacturing, packaging delays are often the biggest reason product launches are postponed