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burgdorferi collagen-binding adhesins began long before the identification of BBA33 as a collagen-binging adhesin (Zhi et al., 2015)

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However, the polyphenols therapeutic potential is becoming more and more evident, enticing the worldwide researchers with a landscape of therapeutic possibilities to uncover the precise and effective biological role of this molecules in counteract oxidative stress, enabling their implementation in preventive healthcare practices, according to the evidence-based dentistry [168]

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MAFLD covers a range of diseases from NAFL with no obvious inflammatory manifestations to NASH, these hepatic steatoses are linked with lobular inflammation, pericyte fibrosis, and apoptosis, and cannot distinguish histologically from alcoholic steatohepatitis [14, 15]

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