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Common Prozac discontinuation symptoms include: Brain zaps (brief, electric shock-like sensations in the head or body) Dizziness and lightheadedness that worsen with quick movement Nausea, stomach cramps, or loose stools Insomnia and vivid or disturbing dreams during sleep Irritability, heightened anxiety, and unexplained shifts in mood Physical fatigue and flu-like symptoms, including sweating Headache and difficulty with concentration or memory Fluoxetine has a half-life of approximately four to six days, with its active metabolite, norfluoxetine, persisting in the system for up to 16 days after the last dose