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doi: 10.1080/15419060600726209
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Appears to interact with nitric oxide pathways and may modulate VEGF and other growth factors in tissue recovery models
doi: 10.1016/j.mimet.2020.105889
Notably, studies have reported that DSIP-mediated analgesia occurs without the tolerance development typically seen with exogenous opioid compounds, suggesting a fundamentally different mechanism of interaction with the opioid system
