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The spliced bZIP60 mRNA is translated, the protein translocates to the nucleus and activates directly UPR genes such as genes encoding chaperones of the HSP70 family called BIPs (luminal-binding proteins)

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To show the outlines of acinar cells, we used Alexa Fluor 488 conjugated Wheat Germ Agglutinin (1:200) as counterstaining (W11261, Thermo Fisher, Waltham, MA, USA)

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