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Retatrutide : This triple agonist (GLP-1 + GIP + glucagon) produced 28.7% weight loss in Phase 3 but introduced a new safety signal: dysesthesia (abnormal skin sensations) in 4.4 to 20.9% of participants at the 12 mg dose depending on trial population

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doi: 10.1038/s41598-019-39170-w

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