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Notably, autophagy inhibition is a contributory mechanism of protein aggregate-induced cardiomyopathies in aging CR-hCryAB Tg mice (Qin et al., 2016), myocardial ischemia-reperfusion mice (Ma et al., 2012), and aging Drosophila with laminopathy (Wang and Cui, 2017)

In the placebo group, a significant 70% increase in intestinal permeability was observed after the gluten challenge in contrast to the AT1001 treated patients in whom no changes in permeability were observed

Research shows that intravascular TF may also be found in neutrophils, eosinophils, and platelets [14]

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M., Dai, Q., Alman, B
