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Lancet 396:186197 Usmani SZ, Quach H, Mateos MV, Landgren O, Leleu X, Siegel D et al (2022) Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): updated outcomes from a randomised, multicentre, open-label, phase 3 study

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Stupnisek M., Franjic S., Drmic D., Hrelec M., Kolenc D., Radic B., Bojic D., Vcev A., Seiwerth S., Sikiric P

Injectable vitamin B12 avoids this limitation by: Delivering a concentrated dose directly into systemic circulation Ensuring near-complete absorption Rapidly increasing serum B12 levels Because of this mechanism, B12 shots are often recommended for moderate to severe deficiencies or when quick correction is required

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The cells are arranged in dense layers that replace the subcutaneous tissue and deep planes