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First, the causes are zone-specific

Meanwhile, PHIP can induce a decrease in beneficial GM, like Lactobacillus , which is responsible for reducing the genotoxicity of this compound 51

[DOI] [PubMed] [Google Scholar] 136.Vanelderen P, Van Zundert J, Kozicz T, Puylaert M, De Vooght P, Mestrum R, et al

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doi:10.1093/ajcn/50.2.301