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Description
The proposed chain of effects looks like this: NNMT inhibited nicotinamide is no longer inactivated by methylation and becomes available for conversion to NAD+

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People with cancer (active or suspected): As mentioned previously, TB4 and TB-500 can promote the growth of new blood vessels, which could support the growth or spread of cancer.36 Professional athletes: TB4 and TB-500 are banned by the World Anti-Doping Agency (WADA)
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