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It exerts anti-inflammatory effects by inhibiting the gene expression of pro-inflammatory cytokines such as IL-1, IL-1, IL-6, and IL-12p35, downregulating the activity of inflammatory enzymes like iNOS and COX-2, and suppressing key factors in inflammation signaling pathways such as NF-B, FOXO3a, and SIRT1(Parvez et al., 2019)

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Molecular Mechanism of Stimulant Treatments In order to obtain a full picture of the MoA of stimulants (MPH and LDX), one must consider not only direct targets but also other molecular mediators known to be modulated by the drugs

Nuciforo, S., & Heim, M

Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network

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