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Maggio A (2007) Light and shadows in the iron chelation treatment of haematological diseases

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Beyond direct antioxidant activity, GSH functions as an obligatory cofactor for a family of enzyme systems that are central to cellular defence: glutathione peroxidases (GPx), which reduce peroxides and lipid hydroperoxides using GSH as the reducing substrate

2017;9(1):E24

doi: 10.3389/fimmu.2019.02993 51 IpWKEHoshiNShouvalDSSnapperSMedzhitovR

In this case, ATO was added after the first 24 hours of treatment with MTX and the number of viable cells was measured 24 hour later