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The authors mentioned that intranasal administration facilitated brain-targeted delivery (DTE % = 314.29%) owing to the nanoscale size and lipid nature of liposomes, which facilitated the transcellular transport of drug molecules via various endocytic pathways in sustentacular and neuronal cells within the olfactory membrane

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Severe side effects are rare but include anaphylaxis (especially in those allergic to cobalt or B)

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Deficiencies in omega-3 fatty acids, vitamin D, B-complex vitamins, and zinc are common in individuals with SUD, and correcting these imbalances has been associated with improvements in mood, cognition, and immune function

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