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This is not a reason to dismiss the compound it is a reason to be honest about what we know and dont know

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The primary mechanism of TB-500 involves binding to G-actin, preventing its polymerization and maintaining a pool of monomeric actin available for rapid cellular reorganization

Interestingly, while you absorb 40 to 50 per cent of vitamin B12 from foods, including fortified foods, the absorption from supplements depends on the dose (EFSA, 2015