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199 Although clinical trials remain limited, early-phase evaluations indicate favorable pharmacokinetics and biosafety

As a brief introduction, binding of epidermal growth factor (EGF) to the extracellular domain of the EGF receptor (EGFR) leads to the assembly and activation of NADPH oxidase (Nox) that, in turn, generates endogenous H 2 O 2 [60]

This process is indispensable for the synthesis of nucleotides that are critical for cell proliferation and growth regulation (169,170)

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A recent comprehensive review found that herbal remedies are safe when used in conjunction with conventional therapy and have positive benefits in controlling the aberrant behaviors and inattentiveness of ASD patients [143,144]