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Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

Agents 48 , 265270 (2016)

These are the types of studies that augment our approach to regenerative orthopedics

As the intimal volume enlarges due to accumulating cells, there is vascular remodeling to lessen protrusion of the lesion into the lumen (Figure 4), thereby decreasing occlusion and the appearance of clinical symptoms for much of the life of the lesion (165-167)

Unlike conventional antidepressants, which often carry a high burden of side effectssuch as sexual dysfunction, weight gain, insomnia, or gastrointestinal disturbancesphytochemicals typically exhibit favorable safety and tolerability profiles [256]

Their primary mechanism of action involves the potent inhibition of presynaptic reuptake pumps for both 5HT and norepinephrine within the CNS