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Role of inflammation in the development of renal damage and dysfunction in angiotensin II-induced hypertension

This pathway is found to be highly dependent on SSP-provided -KG when glutamine metabolism is inhibited [222]

Increased amounts of reactive oxygen species (ROS) in cancer cells may facilitate tumour development, genetic instability, and resistance to programmed cell death (apoptosis) [11, 94, 95]

Endothelial and stromal involvement Endothelial cells exposed to IR upregulate adhesion molecules (Intercellular Adhesion Molecule 1 (ICAM-1), Vascular Cell Adhesion Molecule 1 (VCAM-1), E-selectin), enhancing leukocyte recruitment

Vegetarians and vegans: Since most foods that contain B12 naturally are animal products like meat, eggs and dairy, vegetarians and vegans are at greater risk of developing a B12 deficiency
