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Toxicant Burden and Sensitivities: By heavily upregulating Phase II liver detoxification enzymes (GSTs) and providing direct heavy metal chelation, NAC helps the body safely process and excrete environmental toxins, potentially reducing systemic chemical sensitivities

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Although momentous for tissue repair and regeneration, DAMPs could bring about sterile inflammation ( UA usually exists in the ionic state in body fluids, but in patients with hyperuricemia or gout, it can precipitate into a large number of crystal deposits, and the majority of crystal components are monosodium urate (MSU)
et al.: Methylmalonate excretion in a patient with pernicious anemia (1963) The New England journal of medicine | DOI: 10.1056/NEJM196301172680309

Pueschel, 1990), evidenced by early onset of cataracts and the risk of developing Alzheimer's disease
