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Although oral and injectable routes are widely used for managing these conditions, they suffer from drawbacks such as poor drug targeting to the lungs, susceptibility to first-pass metabolism, and undesirable systemic side effects
[DOI] [PubMed] [Google Scholar] 86.Verhoef P., Steenge G.R., Boelsma E., Van Vliet T., Olthof M.R., Katan M.B
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2009;296:E581E591
