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It supports muscle fiber repair, reduces scar tissue formation, and improves oxygen utilization in healing tissue
Folate must be checked alongside B12, and folate deficiency should never be treated in isolation when B12 is low, because doing so can mask the anaemia while neurological damage progresses

This function theoretically contributes to weight loss
Notably, idiopathic peripheral neuropathy, where no clear cause can be identified, accounts for up to 25% of PN cases

Examples of drugs that can cause interactions with methotrexate are listed below
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