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Contraindications and precautions Consider avoiding DSIP or consulting a physician if: Pregnant or breastfeeding (insufficient safety data) Taking naloxone or other opioid antagonists (may block effects) Using medications metabolized by peptidases (potential interactions) History of immune disorders (theoretical immunogenicity concern) Already using multiple sleep medications Drug interactions Because DSIP degrades via amino-peptidases in blood, medications affecting these enzymes (like the ACE inhibitor captopril) could theoretically alter DSIP metabolism

This is because it takes a really long time, and it may be difficult to portion that type of time commitment before you truly know you enjoy the effects

Recalls & Warnings October 06, 2005 Deceptive Marketing of Supreme Greens" -- Settlement with FTC On October 6, 2005, the Federal Trade Commission (FTC) announced that three individuals and two companies have settled FTC charges over their roles in the deceptive marketing of Supreme Greens, an herbal supplement