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Porter C, Constantin-Teodosiu D, Constantin D, Leighton B, Poucher SM, Greenhaff PL

Hudson S, Tabet N

Diabetes 69(7):1573-87 2020 PMC7306123 Berkson JD, Slichter CK, DeBerg HA, Delaney MA, Woodward-Davis AS, Maurice NJ, Lwo Y, Ko A, Hsu J, Chiu YW, Linsley PS, Dixon D, Prlic M

When a child experiences a metabolic stressorsuch as a fever, dehydration, or an infectionthe sudden spike in toxic acids can temporarily overwhelm the kidneys [8] [7]

As carnitine has a low molecular weight, it is passively filtered across glomeruli

With ongoing advances in research on the gut microbiome and its metabolites, trimethylamine N-oxide (TMAO) has emerged as a significant factor implicated in the progression of heart failure (HF) and is linked to a poor prognosis in HF patients