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The diversity of available animal systems, from rodents suited for genetic manipulation and mechanistic exploration to large animal models such as dogs and nonhuman primates that offer closer anatomical, microbial, and immunological similarities to humans, provides a flexible framework in which earlystage hypotheses can be refined before being tested in more clinically relevant settings

Limitations of this review that may have limited the number of potential search results include utilization of a small number of databases, not using additional synonymous search terms, and only including unrestricted access resources

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Paul BD, Snyder SH

Curcumin analogue L48H37 suppresses human osteosarcoma invasion via inhibition of uPA and JAK/STAT signaling