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Interestingly, this promising technology was adapted later to prepare a CD-based rotaxane as a near infrared-triggered drug release for in vivo evaluation 57
1, 25-Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: Implication for behavioral influences of vitamin D
Hamilton Poland
Additionally, mitochondrial ROS-induced oxidation of GSDMD is a crucial mechanism facilitating GSDMD cleavage, which in turn drives NLRP3-dependent pyroptosis in macrophage [144]
To ensure the adaptive metabolic responses of cells in hypoxia, this mechanism required the HIF-1-dependent expression of BNIP3 and constitutive expression of Beclin-1 and Atg5, which lowered mitochondrial numbers and prevented a increase in ROS [29]
[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Jiang T., Li C.Y., Teng Y.X., Zhang R.H., Yan Y.J
