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When we consider GHK-Cu, its copper ion also adds another layer of complexity

Tissue Remodeling: Studies suggest a role for GHK and copper peptides in tissue remodeling, although the optimal conditions for its use are still being determined (7)

Causes of B12 Deficiency Although the requirements of B12 are quite small, it has a complicated absorption process in the digestive tract and, therefore, certain conditions make a B12 deficiency more common

And the answer is both simple and nuanced