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PI3K/mTOR inhibitors induce synergistic anti-proliferative and pro-apoptotic effects by inhibiting the kinase activity of the CDK/cyclin complex and, consequently, preventing phosphorylation of the Rb protein (Cretella et al
Yugi, K., Ohno, S., Krycer, J
doi: 10.1371/journal.pone.0115694, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Chen P
Kochanczyk, T., Drozd, A
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Neutrophil extracellular traps and extracellular DNA and histone-DNA complexes are increased in dogs with IMHA (Jeffrey et al 2015, Lawson et al 2018)
