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Studies, including research from the National Institute on Drug Abuse (NIDA), show that repeated opioid exposure leads to structural brain changes, increasing the risk of addiction

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10.1093/nar/gkr1095 128 StiversJ

(2014) Carrier-mediated cocaine transport at the bloodbrain barrier as a putative mechanism in addiction liability

Six weeks after therapy, the study revealed that vitamin D supplementation may considerably lower the pro-inflammatory IL-6 and consequently vitamin D should be used as a supplement in the treatment of pneumonia patients [61]