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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Modulation of C-reactive protein, tumor necrosis factor-, and adiponectin by diet, exercise, and weight loss

The market growth is primarily driven by its ability to preserve muscles glycogen and promote fat oxidation

It works as a potent antioxidant, improves blood flow to nerves, and enhances glucose uptake all of which can help reduce burning, tingling, and pain associated with neuropathy.1 Clinical trials have shown consistent benefits at 600mg per day, particularly when taken long-term and under medical supervision.7 Benfotiamine (300mg per serving) Benfotiamine is a fat-soluble form of vitamin B1 (thiamine) with significantly better bioavailability than standard thiamine.46 It plays a central role in glucose metabolism and helps prevent the accumulation of harmful byproducts like advanced glycation end products (AGEs), which contribute to nerve damage in diabetes

34 In the mitochondria, it is involved in numerous bioenergetic reactions, including a critical step bridging glycolysis and the citric acid cycle