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Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)

However, high levels of extracellular Mn 2+ decrease the expression of GLAST and induce astrocyte apoptosis (Ingersoll et al

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J Inherit Metab Dis 2014, 37 (4), 553563

Also, a meta-regression analysis was conducted to evaluate the treatment duration and ALC daily dose as moderators in the HDRS and BDI datasets

JP patent 60,244,299 Ochiai H (1987) Production of glutathione by photofermentation: use of thermophilic cyanobacteria