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1 L-Carnitine has also been associated with a significant reduction in all-cause mortality, ventricular arrhythmias, and anginal symptoms in patients experiencing acute myocardial infarction

The THEM5 gene has also been identified as ACOT15

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Further regulation of cholesterol biosynthesis is exerted by sterol intermediates in cholesterol biosynthesis, such as lanosterol and 24,25dehydrolanosterol (dimethyl-sterols), and by cholesterol sulfate via accelerating degradation of the biosynthetic enzymes such as HMG-CoA reductase, while side-chain oxysterols like 25hydroxycholesterol interfere by suppressing the activation of SREBP-2 through binding to an oxysterol-sensing protein in the endoplasmic reticulum