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doi:10.1159/000500306 Subramanyam AA, Kedare J, Singh OP, Pinto C

HGF is secreted by mesenchymal cells as a single-chain, biologically inert precursor and is converted into its bioactive form when extracellular proteases cleave the bond between Arg494 and Val495

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Separately, RegeneRx's ophthalmic formulation RGN-259 completed Phase 3 trials (ARISE-1 and ARISE-2) for dry eye with mixed results

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Cellular profile for lung regeneration The proteomics results suggested that the protein pathways were enriched in ECM remodeling and epithelial polarization, implying that multiple cell types might be involved in the signal regulation
