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With this biotransformation, liver detoxification, a long-standing barrier in nanomedicine translation, can be turned into a bridge toward maximizing targeting and minimizing nanotoxicity

This is due to the fact that intestinal calcium absorption occurs via both paracellular (between cells) and transcellular (through cells) mechanisms

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This is often due to a poor diet and less stomach acid, which the body needs to absorb B12 from food

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This crucial phase of the malady, in analogy with other viral infections and to a widely accepted pharmacological praxis, should be timely treated either with etiotropic drugs (which in COVID-19 case are still lacking) as well as with host-directed agents to manage/prevent the symptoms (Sestili and Stocchi, 2020)