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Whether the alternative pattern would work as well isnt known

The supraspinatus tendon, the most commonly injured rotator cuff structure, has a particularly poor vascular zone near its insertion point on the humerus

These include the bell-shaped dose-response curve, central effects after peripheral administration, a delayed and prolonged time course, and some penetration of the blood-brain barrier in essentially intact form

It is conceivable that BPC-157 may exhibit some engagement with the NO mechanism, possibly providing a safeguard for the endothelium and perhaps encouraging angiogenic behaviors by fostering the development of new circulatory routes