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Exogenous oestrogen in combined oral contraceptive pills and hormone replacement therapy directly enhances Candida adherence to mucosal surfaces via oestrogen receptor-mediated upregulation of Candida adhesins

The discovery of the immunosuppressive capabilities of MSCs significantly advanced clinical studies for the treatment of various immune-mediated disorders

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Beyond the immediate nerve injury, the surgical environment itself contributes through associated factors like the intensity of acute postoperative pain, which acts as a potent nociceptive barrage driving central sensitization, and potentially inadequate perioperative analgesia [4]