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doi: 10.1111/jsm.12312
Theoretically, the use of pure -adrenergic receptor agonists, such as isoproterenol, and, to a lesser extent, dobutamine, is controversial as this may worsen hypotension mediated by 2-adrenergic receptor agonist-induced peripheral vasodilation
Four patients changed in the opposite direction
PMID: 29168138 Solvent & Solubility In Vitro : H 2 O : 50 mg/mL ( 310.17 mM ) * "" means soluble, but saturation unknown
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