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Des tudes prcliniques chez l'animal (modles murins de cancer du poumon, de mlanome et de carcinome hpatocellulaire) ont montr que la NAC pouvait acclrer la croissance tumorale ou favoriser la dissmination mtastatique dans certains contextes

& Christman, K

Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuit

Orphanet J Rare Dis 4:3

Abstract Background Various antiepileptic drugs can potentially cause psychiatric side effects in patients with epilepsy, but the precise mechanism of these actions remains unknown

The current challenge is to understand the temporal and spatial interactions among these cell death pathways and to identify context-specific targets that can be safely and effectively modulated in patients