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Ferroptosis promotes the progression of neurodegenerative diseases, while the expression of Nrf2 and its target genes (Ho-1, Nqo-1, and Trx) has been declined with aging
Hakim A, OCallaghan C, De Wandele I, Stiles L, Pocinki A, Rowe P

Our recent studies showed that compared to those in control cells, the protein levels of H3K9me1, H3K9me2, and H3K9me3 were increased in HASMCs treated with ferroptosis inducers (cystine deprivation, IKE, or RSL3)

Seiwerth et al., 2018)
85 YeY.LiZ.XingD