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Some people use liposomal glutathione supplements with the belief that it can help lighten skin tone and reduce hyperpigmentation

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Ferenczi EA, Zalocusky KA, Liston C, Grosenick L, Warden MR, Amatya D et al (2016)

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Among the important enzyme-mediated cellular processes that use GSH as a cofactor is the GSH-dependent reduction of hydrogen peroxide and other peroxides catalyzed by glutathione peroxidase (Figure 2)

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The secreted peroxidase becomes part of the matrix and probably stabilizes it by cross-linking

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Who not to refer: How to refer: Patients needing further investigation should be referred urgently to the Department of Gastroenterology WGH, St Johns or RIE as indicated above

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Causes: Venoocclusive disease: Chemotherapeutic agents, bush tea Peliosis hepatis: Anabolic steroids Hepatic vein thrombosis: Oral contraceptives Neoplasm [edit] Neoplasms have been described with prolonged exposure to some medications or toxins

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