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Erythrocytes express Ca 2+ -activated K + channels (KCa3.1 encoded by KCNN4 ), also called Gardos channels [107]
Top row: non-injected embryos not stained with primary antibody
This makes it part of a unique class of peptides called mitochondrial-derived peptides (MDPs) small proteins that act as signaling molecules to regulate metabolism and cellular stress responses
While the mechanism of the canonical reaction was uncovered decades ago, new studies are highlighting the myriad of regulatory mechanisms presented to this enzyme
Bone, 2013
