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BCAAs, such as leucine, isoleucine, and valine, are metabolized primarily in the muscles, and the byproducts of their metabolism contribute to muscle fatigue and discomfort

9 These findings raise the possibility that other dietary nutrients possessing a trimethylamine structure may also generate TMAO from gut microbiota and promote accelerated atherosclerosis

Risks of TMAO In 1984 Rebouche et al

Targeting metabolism in aortic aneurysm and dissection: from basic research to clinical applications

80 McKennaC
