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Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

R.KnigM.HuismanW.DaleboutT.TakT.et al

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Cell 9 (5) (1998) 10811091

These approaches included anti-IGF-1R monoclonal antibodies (mAbs), IGF-1R tyrosine kinase inhibitors (TKIs), IGF-1/2 blocking mAbs, IGF ligand-TRAPs, recombinant IGFBPs and pregnancy-associated plasma protein-A (PAPP-A) inhibition [54,55]

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