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Over the past decade, preclinical and clinical studies have demonstrated their efficacy in treating immune-inflammatory disorders, respiratory diseases, musculoskeletal defects, cardiocerebral vascular pathologies, neurodegenerative conditions, metabolic disorders, and neoplastic diseases

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, Lake, J

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doi: 10.1021/acs.jmedchem.4c00596

It has been proposed that mutations in FP may represent an important cause of iron overload among African-Americans.10 Pathogenesis Despite the recent advances, our understanding of iron homeostasis and pathogenesis of hemochromatosis remain incomplete