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The narrative format was selected to accommodate heterogeneous evidence spanning preclinical mechanisms, clinical trials, and translational barriers where systematic synthesis would be inappropriate

Glutathione plays an important role in the detoxification of reactive oxygen species (ROS) in the central nervous system, where it directly quenches radicals in nonenzymatic reactions and reduces peroxides generated by glutathione peroxidase

We found that, as we had observed for DeepMet, molecules generated more frequently by the non-pretrained model were disproportionately metabolite-like