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Extensive work has been done on the whipworm Trichuris , but other helminths, including Schistosoma, Trichinella, Heligmosomoides , and Ancylostoma , have also been explored for pre-clinical and animal studies
Studies have shown that exogenous SAM is utilized for phospholipid methylation on the outer surface of the plasma membrane

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The color change of the AuNP solution can reveal experimental results more conveniently, and the color-based assay can be more easily operated
