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Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy

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When the Kimura distribution was applied to analysis of heteroplasmy transmission of the tRNA Met 3875delC mutation, even for more central p 0 values where the effects on b are minimized, quite large sample sizes were required to show the directionality associated with selection (Freyer et al

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J., OMaille, G., Abagyan, R

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