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In more severe cases, the zonules holding the IOL- capsular bag complex in position within the eye completely rupture, leaving this structure to float freely within the eye which leads to a major disruption of the eyes optical power and compromises the health and function of other ocular structures including the cornea, retina, ciliary body/trabecular meshwork, and iris if not surgically corrected (330, 333)

hence there is a need for more detailed research on its cellular signaling pathways as well as its pharmacological targets

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Notably, metabolic byproducts of phthalate compounds, including DEHP, have been detected in diverse population groups, encompassing both children and pregnant women 2,3

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